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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAPDC1A
All Species:
24.55
Human Site:
T75
Identified Species:
38.57
UniProt:
Q5VZY2
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VZY2
NP_001025230.1
271
30395
T75
V
V
K
I
I
R
R
T
D
K
T
E
I
K
E
Chimpanzee
Pan troglodytes
XP_001170623
223
25141
L28
V
I
A
F
L
S
P
L
S
L
I
F
L
A
K
Rhesus Macaque
Macaca mulatta
XP_001092746
343
37863
P134
Y
V
E
A
E
Y
F
P
T
K
P
M
F
V
I
Dog
Lupus familis
XP_535038
333
36609
T137
V
V
K
I
I
R
R
T
D
K
T
E
I
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBU9
271
30425
T75
V
V
K
I
I
R
R
T
D
K
T
E
I
K
E
Rat
Rattus norvegicus
O08564
282
31978
T73
F
C
I
I
V
M
I
T
G
E
T
L
S
V
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514919
461
51675
T81
V
V
K
I
I
R
R
T
D
K
T
E
I
K
E
Chicken
Gallus gallus
XP_426544
322
36285
T126
V
V
K
I
I
R
R
T
D
K
T
E
I
K
E
Frog
Xenopus laevis
Q6GQ62
226
25153
V31
F
L
T
P
L
S
V
V
A
L
A
R
L
F
W
Zebra Danio
Brachydanio rerio
XP_002664129
282
31516
T82
V
V
K
I
I
Q
R
T
D
R
T
E
I
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623887
268
30640
I72
L
V
F
T
M
P
V
I
V
I
F
C
V
F
L
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
F126
F
V
R
L
L
T
Y
F
G
Y
S
Q
I
G
F
Sea Urchin
Strong. purpuratus
XP_787511
258
29394
V62
A
I
L
V
P
L
C
V
I
T
I
F
S
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
Y94
Y
F
I
R
N
D
V
Y
D
L
H
H
A
I
L
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
H91
S
I
L
A
D
R
R
H
L
I
F
I
L
Y
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
48
77.7
N.A.
99.2
25.5
N.A.
48.1
77.3
52.4
71.2
N.A.
N.A.
47.9
24.3
46.1
Protein Similarity:
100
64.9
60
79.8
N.A.
99.2
41.1
N.A.
53.3
80.4
63.4
83.6
N.A.
N.A.
66.7
39.8
64.2
P-Site Identity:
100
6.6
13.3
100
N.A.
100
20
N.A.
100
100
0
86.6
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
100
33.3
20
100
N.A.
100
33.3
N.A.
100
100
20
100
N.A.
N.A.
26.6
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
31.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.4
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
14
0
0
0
0
7
0
7
0
7
7
0
% A
% Cys:
0
7
0
0
0
0
7
0
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
0
7
7
0
0
47
0
0
0
0
0
0
% D
% Glu:
0
0
7
0
7
0
0
0
0
7
0
40
0
0
40
% E
% Phe:
20
7
7
7
0
0
7
7
0
0
14
14
7
14
7
% F
% Gly:
0
0
0
0
0
0
0
0
14
0
0
0
0
7
0
% G
% His:
0
0
0
0
0
0
0
7
0
0
7
7
0
0
0
% H
% Ile:
0
20
14
47
40
0
7
7
7
14
14
7
47
7
7
% I
% Lys:
0
0
40
0
0
0
0
0
0
40
0
0
0
40
7
% K
% Leu:
7
7
14
7
20
7
0
7
7
20
0
7
20
7
14
% L
% Met:
0
0
0
0
7
7
0
0
0
0
0
7
0
0
7
% M
% Asn:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
7
7
7
7
7
0
0
7
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
0
0
0
0
0
7
0
0
0
% Q
% Arg:
0
0
7
7
0
40
47
0
0
7
0
7
0
0
0
% R
% Ser:
7
0
0
0
0
14
0
0
7
0
7
0
14
0
0
% S
% Thr:
0
0
7
7
0
7
0
47
7
7
47
0
0
0
7
% T
% Val:
47
60
0
7
7
0
20
14
7
0
0
0
7
14
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
14
0
0
0
0
7
7
7
0
7
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _